Raman spectroscopy - advanced optical analysis technology
Boost plant safety, ensure product quality, and optimize operations. Raman spectroscopy measures the composition and molecular structure of your samples from lab-to-process in real time.
Specs at a glance
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Sampling probe compatibility
Raman Rxn-10
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Sampling sleeve compatibility
Raman bio sleeve
Field of application
The bio multi optic is a critical part for easy, reliable, real-time bioprocess measurements with maximum sterility and efficiency. The non-contact multi optic features a patented self-aligning lens for top spectral quality and reproducibility. It pairs with the Rxn-10 probe and connects to an autoclavable (or gamma sterilizable), disposable bio sleeve via an easy snap-in-place design. The system reduces maintenance and cross-contamination risk for reusable or single-use benchtop bioreactors.
Benchtop bioreactors to measure glucose, lactate, amino acids, cell density, titer and more
Benchtop fermenters to measure glycerol, methanol, ethanol, sorbitol, biomass, and more
Use with flow assembly CYA680 for select downstream bioprocessing applications
Benefits
Improved ease of use and reduced maintenance for bioprocessing
Simplified workflow for greater process efficiency – swap out probes mid-batch, use multiple sleeves in the same reactor for simplified redundancy, and calibrate / verify probes at any time
Optimized spectral performance when used with a compatible bio sleeve
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- Reliable, robust and low-maintenance
Technical excellence
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Specialized products
- Designed for demanding applications
Technical excellence
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| FLEX selections | Technical excellence | Simplicity |
|---|---|---|
Fundamental selection Meet your basic measurement needs |
Technical excellence
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Simplicity
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Lean selection Handle your core processes easily |
Technical excellence
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Simplicity
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Extended selection Optimize your processes with innovative technologies |
Technical excellence
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Xpert selection Master your most challenging applications |
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Could also interest you
38 documents
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Technical Information (TI)
Accessory optics for the Rxn-10 probe Technical Information
System design and specifications for Rxn-10 probe optics:
Raman immersion optics (KIO1),
non-contact optics (KNCO1), bIO-Optics (KLBIO1),
bio multi optics (KRBMO), bio sleeves (KRBSL),
and Raman optic system for single use (KRSU1)EN 31/05/202303/08/2022Language:
English
Version:
31/05/2023
File size:
467.9 KB
File name:
TI01635CEN_0322.pdf
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Technical Information (TI)
Multi optic calibration and verification kit Technical Information
System design and specifications for the multi optic calibration
and verification kitEN 26/06/2023Language:
English
Version:
26/06/2023
File size:
478.7 KB
File name:
TI01719CEN_0123 Multi optic calibration and verification kit.pdf
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Technical Information (TI)
Rxn-10 Raman spectroscopic probe Technical Information
System design and specifications for the Raman Rxn-10 probe
EN 08/09/202513/11/202431/05/202313/09/202208/09/2021Language:
English
Version:
08/09/2025
File size:
949 KB
File name:
TI01629CEN_0525.pdf
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Operating Instruction (BA)
Accessory optics for the Rxn-10 probe Operating Instructions
Commissioning, operation, and maintenance details
for Rxn-10 probe optics: Raman immersion optics (KIO1),
non-contact optics (KNCO1), bIO-Optics (KLBIO1),
bio multi optics (KRBMO), bio sleeves (KRBSL)
and Raman optic system for single use (KRSU1)EN 31/05/202303/08/202214/09/2021Language:
English
Version:
31/05/2023
File size:
1.8 MB
File name:
BA02171CEN_0322.pdf
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Operating Instruction (BA)
Multi optic calibration and verification kit Operating Instructions
Commissioning, operation, and maintenance details for the
multi optic calibration and verification kitEN 26/06/2023Language:
English
Version:
26/06/2023
File size:
996.4 KB
File name:
BA02294CEN_0123 Multi optic calibration and verification kit.pdf
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Operating Instruction (BA)
Rxn-10 Raman spectroscopic probe Operating Instructions
Commissioning, operation, and maintenance details
for the Raman Rxn-10 probeEN 08/09/202502/12/202431/05/202313/09/202208/09/2021Language:
English
Version:
08/09/2025
File size:
1.8 MB
File name:
BA02160CEN_0525.pdf
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Short Instruction (KA)
Rxn-10 Raman spectroscopic probe Brief Operating Instructions
Quick start guide for the Raman Rxn-10 probe
EN 02/12/202431/05/202313/09/202208/09/2021Language:
English
Version:
02/12/2024
File size:
1.6 MB
File name:
KA01546CEN_0424.pdf
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Short Instruction (KA)
Accessory optics for the Rxn-10 probe Brief Operating Instructions
Quickstart guide for Rxn-10 probe optics:
Raman immersion optics (KIO1),
non-contact optics (KNCO1), bIO-Optics (KLBIO1),
bio multi optics (KRBMO), bio sleeves (KRBSL),
and Raman optic system for single use (KRSU1)EN 31/05/202303/08/202214/09/2021Language:
English
Version:
31/05/2023
File size:
1 MB
File name:
KA01551CEN_0322.pdf
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PU (Publication)
Biopharma 4.0 model graphic
Graphic illustrating the core elements of Biopharma 4.0 including
product lifecycle stages, role of PAT/QbD, and 12 key advanced
technologies for scientists and process engineers in the Life
Sciences, applicable to Raman spectroscopy systems (Raman
Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and
sleeve, flow cell and flow bench, Raman optic system for single
use, and Raman calibration & verification kits).Language:
English
Version:
22/05/2025
File size:
481.6 KB
File name:
PU01614CEN_0125.pdf
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PU (Publication)
Top must-read Biopharma 4.0 articles - Stay informed about the latest research embracing Biopharma 4.0 principles
A list of published technical articles related to Biopharma 4.0
topics with recommendations from Life Science industry experts
at Endress+Hauser.Language:
English
Version:
26/06/2025
File size:
363.4 KB
File name:
PU01611CEN_0125.pdf
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PU (Publication)
Endress+Hauser - ライフサイエンス技術のワンストップパートナー
Endress+Hauserが、ライフサイエンス分野の専門知識と、ラマン分
光システム（Raman Rxn2、Raman Rxn4、Rxn-10、Rxn-45、Rxn-46、
バイオマルチオプティックおよびスリーブ、フローフィル、フロー
ベンチ、シングルユース用Ramanオプティックシステム）や水質分
析センサ技術（Liquiline CM44P、CM442、OUSAF44、OUSBT66、
Memosens CPS61E、CLS82E、COS81E、CLS82E）などの信頼性の高い
インラインおよびリアルタイム測定技術によって、世界トップクラ
スのバイオ医薬品メーカーから信頼されている理由を強調したグラ
フィック。Language:
Japanese
Version:
04/10/2024
File size:
2.5 MB
File name:
PU01585CJA_0124_Graphic_EH biopharma trust.pdf
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PU (Publication)
ライフサイエンスにおけるラボからプロセスまでの監視と制御 バイオプロセスの物理的・化学的特性の信頼性の高い測定
この製品リストは、ライフサイエンス業界におけるバイオプロセス
用途向けに、光学分析および液体分析の両方から提供される分析機
器をまとめたものです。含まれる製品には、Raman Rxn2アナライザ
、Raman Rxn4アナライザ、Rxn-10プローブ、バイオマルチオプティ
ックおよびバイオスリーブ、ラマンフローアセンブリ、Rxn-45プロ
ーブ、Rxn-46プローブ、シングルユース向けラマンオプティックシ
ステム、Memosens CPS61E、Memosens COS81E、OUSBT66、Memosens
CPS77E、Memosens CLS82E、OUSAF44、Memosens CPS11E、Memosens
CLS16E、TOCアナライザーCA79、Liquiline変換器プラットフォーム
、およびMemobaseソフトウェアが含まれています。Language:
Japanese
Version:
24/08/2025
File size:
1.2 MB
File name:
PU01484CJA_0224_Lab-to-Process Control in Life Sciences.pdf
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PU (Publication)
Prioritize scalability for an efficient biopharmaceutical product development lifecycle
This technical paper studies the importance of scalability as a
competitive advantage in bioprocessing in the Life Science industry,
and Endress+Hauser's scalable Raman systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology and Liquid Analysis portfolio
(Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and
Memosens CPS61E, CLS82E, COS81E, CLS82E).Language:
Czech
Version:
06/09/2024
File size:
381.4 KB
File name:
PU01584CEN_0124_cz_view.pdf
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PU (Publication)
Biopharma 4.0 model graphic (full version)
Expanded version of a graphic illustrating the core elements of
Biopharma 4.0 including product lifecycle stages, role of
PAT/QbD, and 12 key advanced technologies for scientists and
process engineers in the Life Sciences, applicable to Raman
spectroscopy systems (Raman Rxn2, Raman Rxn4, Rxn-10,
Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow
bench, Raman optic system for single use, and Raman calibration
& verification kits).Language:
English
Version:
22/05/2025
File size:
29.1 MB
File name:
PU01613CEN_0125.pdf
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PU (Publication)
効率的なバイオ医薬品の製品開発ライフサイクルのために拡張性を優先
この技術文書では、ライフサイエンス産業におけるバイオプロセス
の競争優位性としての拡張性の重要性と、Endress+Hauserの拡張性
のあるラマンシステム（Raman Rxn2、Raman Rxn4、Rxn-10、Rxn-45
、Rxn-46、バイオマルチオプティックおよびスリーブ、フローフィ
ル、フローベンチ、シングルユース用Ramanオプティックシステム）
、水質分析センサ技術、および水質分析製品ラインナップ
（LiquilineCM44P、CM442、OUSAF44、OUSBT66、Memosens CPS61E、
CLS82E、COS81E、CLS82E）について考察しています。Language:
Japanese
Version:
04/10/2024
File size:
1.2 MB
File name:
PU01584CJA_0124_Scalability in biopharma development.pdf
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PU (Publication)
ラマン校正および検証キット ラボからプロセスへの拡張性を実現するラマン分光計システムの校 正と検証のために必要なものすべて
バイオマルチオプティック／シングルユースオプティックおよびラ
マンフローアセンブリ（フローベンチとフローセルを含む）用のラ
マン校正および検証キットの概要です。これらのキットは、Kaiser
ラマンテクノロジーを搭載したRxn-10プローブおよびRaman Rxn2 /
Rxn4アナライザーと併用し、バイオプロセスの上流および下流工
程で使用されます。Language:
Japanese
Version:
13/08/2025
File size:
2.5 MB
File name:
PU01518CJA_0122_Raman calibration and verification kits.pdf
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PU (Publication)
The Biopharma 4.0 glossary - Test your Biopharma 4.0 IQ
A list of definitions and sources for frequently used terms and
abbreviations in the biopharmaceutical industry related to
Biopharma 4.0.Language:
English
Version:
17/06/2025
File size:
445 KB
File name:
PU01610CEN_0125.pdf
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PU (Publication)
Lab-to-process monitoring & control in Life Sciences - Reliable measurement of bioprocess physical and chemical properties
A combined product list of analysis offerings from both Optical Analysis
and LIquid Analysis for bioprocessing applications in the life science
industry (including Raman Rxn2 analyzer, Raman Rxn4 analyzer,
Rxn-10 probe, bio multi optic and bio sleeve, Raman flow assembly,
Rxn-45 probe, Rxn-46 probe, Raman optic system for single use,
Memosens CPS61E, Memosens COS81E, OUSBT66, Memosens CPS61E,
Memosens CPS77E, Memosens CLS82E, OUSAF44, Memosens CPS11E,
Memosens CLS16E, TOC Analyzer CA79, Liquiline transmitter platform, and
Memobase software).Language:
English
Version:
11/04/2024
File size:
776.1 KB
File name:
PU01484CEN_0224.pdf
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PU (Publication)
Raman calibration and verification kits - Everything needed to calibrate and verify your Raman analyzer system for lab-to-process scalability
An overview of the Raman calibration and verification kits for
the bio multi optic / single use optic and the Raman flow assembly
(includes the flow bench and flow cell). These kits are to be used in
conjunction with the Rxn-10 probe and Raman Rxn2 / Rxn4 analyzer
for upstream and downstream bioprocessing (powered by Kaiser
Raman technology).Language:
English
Version:
13/12/2023
File size:
2.1 MB
File name:
PU01518CEN_0223.pdf
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PU (Publication)
Endress+Hauser - your one-source Life Sciences technology partner
Graphic highlighting why Endress+Hauser is trusted by the
world's top biopharmaceutical manufacturers for its Life
Sciences expertise and reliable inline, real-time measurement
technologies like Raman spectroscopy systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology (Liquiline CM44P, CM442 and
OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E,
CLS82E).Language:
Czech
Version:
06/09/2024
File size:
353 KB
File name:
PU01585CEN_0124_cz_view.pdf
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