Raman spectroscopy - advanced optical analysis technology
Boost plant safety, ensure product quality, and optimize operations. Raman spectroscopy measures the composition and molecular structure of your samples from lab-to-process in real time.
Specs at a glance
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Sampling probe compatibility
Raman Rxn-10
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Sampling sleeve compatibility
Raman bio sleeve
Field of application
The bio multi optic is a critical part for easy, reliable, real-time bioprocess measurements with maximum sterility and efficiency. The non-contact multi optic features a patented self-aligning lens for top spectral quality and reproducibility. It pairs with the Rxn-10 probe and connects to an autoclavable (or gamma sterilizable), disposable bio sleeve via an easy snap-in-place design. The system reduces maintenance and cross-contamination risk for reusable or single-use benchtop bioreactors.
Benchtop bioreactors to measure glucose, lactate, amino acids, cell density, titer and more
Benchtop fermenters to measure glycerol, methanol, ethanol, sorbitol, biomass, and more
Use with flow assembly CYA680 for select downstream bioprocessing applications
Benefits
Improved ease of use and reduced maintenance for bioprocessing
Simplified workflow for greater process efficiency – swap out probes mid-batch, use multiple sleeves in the same reactor for simplified redundancy, and calibrate / verify probes at any time
Optimized spectral performance when used with a compatible bio sleeve
Extended selection
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High-end products
- Highly functional and convenient
Technical excellence
Simplicity
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Standard products
- Reliable, robust and low-maintenance
Technical excellence
Simplicity
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Specialized products
- Designed for demanding applications
Technical excellence
Simplicity
Variable
| FLEX selections | Technical excellence | Simplicity |
|---|---|---|
Fundamental selection Meet your basic measurement needs |
Technical excellence
|
Simplicity
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Lean selection Handle your core processes easily |
Technical excellence
|
Simplicity
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Extended selection Optimize your processes with innovative technologies |
Technical excellence
|
Simplicity
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Xpert selection Master your most challenging applications |
Technical excellence
|
Simplicity
Variable |
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Success stories
Could also interest you
29 documents
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Technical Information (TI)
Multi optic calibration and verification kit Technical Information
System design and specifications for the multi optic calibration
and verification kitEN 26/06/2023Language:
English
Version:
26/06/2023
File size:
478.7 KB
File name:
TI01719CEN_0123 Multi optic calibration and verification kit.pdf
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Technical Information (TI)
Accessory optics for the Rxn-10 probe Technical Information
System design and specifications for Rxn-10 probe optics:
Raman immersion optics (KIO1),
non-contact optics (KNCO1), bIO-Optics (KLBIO1),
bio multi optics (KRBMO), bio sleeves (KRBSL),
and Raman optic system for single use (KRSU1)EN 31/05/202303/08/2022Language:
English
Version:
31/05/2023
File size:
467.9 KB
File name:
TI01635CEN_0322.pdf
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Technical Information (TI)
Rxn-10 Raman spectroscopic probe Technical Information
System design and specifications for the Raman Rxn-10 probe
EN 13/11/202431/05/202313/09/202208/09/2021Language:
English
Version:
13/11/2024
File size:
929.9 KB
File name:
TI01629CEN_0424.pdf
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Operating Instruction (BA)
Accessory optics for the Rxn-10 probe Operating Instructions
Commissioning, operation, and maintenance details
for Rxn-10 probe optics: Raman immersion optics (KIO1),
non-contact optics (KNCO1), bIO-Optics (KLBIO1),
bio multi optics (KRBMO), bio sleeves (KRBSL)
and Raman optic system for single use (KRSU1)EN 31/05/202303/08/202214/09/2021Language:
English
Version:
31/05/2023
File size:
1.8 MB
File name:
BA02171CEN_0322.pdf
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Operating Instruction (BA)
Multi optic calibration and verification kit Operating Instructions
Commissioning, operation, and maintenance details for the
multi optic calibration and verification kitEN 26/06/2023Language:
English
Version:
26/06/2023
File size:
996.4 KB
File name:
BA02294CEN_0123 Multi optic calibration and verification kit.pdf
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Operating Instruction (BA)
Rxn-10 Raman spectroscopic probe Operating Instructions
Commissioning, operation, and maintenance details
for the Raman Rxn-10 probeEN 02/12/202431/05/202313/09/202208/09/2021Language:
English
Version:
02/12/2024
File size:
1.2 MB
File name:
BA02160CEN_0424.pdf
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Short Instruction (KA)
Rxn-10 Raman spectroscopic probe Brief Operating Instructions
Quick start guide for the Raman Rxn-10 probe
EN 02/12/202431/05/202313/09/202208/09/2021Language:
English
Version:
02/12/2024
File size:
1.6 MB
File name:
KA01546CEN_0424.pdf
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Short Instruction (KA)
Accessory optics for the Rxn-10 probe Brief Operating Instructions
Quickstart guide for Rxn-10 probe optics:
Raman immersion optics (KIO1),
non-contact optics (KNCO1), bIO-Optics (KLBIO1),
bio multi optics (KRBMO), bio sleeves (KRBSL),
and Raman optic system for single use (KRSU1)EN 31/05/202303/08/202214/09/2021Language:
English
Version:
31/05/2023
File size:
1 MB
File name:
KA01551CEN_0322.pdf
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PU (Publication)
Prioritize scalability for an efficient biopharmaceutical product development lifecycle
This technical paper studies the importance of scalability as a
competitive advantage in bioprocessing in the Life Science industry,
and Endress+Hauser's scalable Raman systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology and Liquid Analysis portfolio
(Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and
Memosens CPS61E, CLS82E, COS81E, CLS82E).Language:
Czech
Version:
06/09/2024
File size:
381.4 KB
File name:
PU01584CEN_0124_cz_view.pdf
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PU (Publication)
Endress+Hauser - your one-source Life Sciences technology partner
Graphic highlighting why Endress+Hauser is trusted by the
world's top biopharmaceutical manufacturers for its Life
Sciences expertise and reliable inline, real-time measurement
technologies like Raman spectroscopy systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology (Liquiline CM44P, CM442 and
OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E,
CLS82E).Language:
English
Version:
27/06/2024
File size:
1.9 MB
File name:
PU01585CEN_0124.pdf
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PU (Publication)
Endress+Hauser - ライフサイエンス技術のワンストップパートナー
Endress+Hauserが、ライフサイエンス分野の専門知識と、ラマン分
光システム（Raman Rxn2、Raman Rxn4、Rxn-10、Rxn-45、Rxn-46、
バイオマルチオプティックおよびスリーブ、フローフィル、フロー
ベンチ、シングルユース用Ramanオプティックシステム）や水質分
析センサ技術（Liquiline CM44P、CM442、OUSAF44、OUSBT66、
Memosens CPS61E、CLS82E、COS81E、CLS82E）などの信頼性の高い
インラインおよびリアルタイム測定技術によって、世界トップクラ
スのバイオ医薬品メーカーから信頼されている理由を強調したグラ
フィック。Language:
Japanese
Version:
04/10/2024
File size:
2.7 MB
File name:
PU01585CJA_0124_Graphic_EH biopharma trust.pdf
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PU (Publication)
Prioritize scalability for an efficient biopharmaceutical product development lifecycle
This technical paper studies the importance of scalability as a
competitive advantage in bioprocessing in the Life Science industry,
and Endress+Hauser's scalable Raman systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology and Liquid Analysis portfolio
(Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and
Memosens CPS61E, CLS82E, COS81E, CLS82E).Language:
English
Version:
27/06/2024
File size:
753.7 KB
File name:
PU01584CEN_0124.pdf
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PU (Publication)
Raman calibration and verification kits - Everything needed to calibrate and verify your Raman analyzer system for lab-to-process scalability
An overview of the Raman calibration and verification kits for
the bio multi optic / single use optic and the Raman flow assembly
(includes the flow bench and flow cell). These kits are to be used in
conjunction with the Rxn-10 probe and Raman Rxn2 / Rxn4 analyzer
for upstream and downstream bioprocessing (powered by Kaiser
Raman technology).Language:
English
Version:
13/12/2023
File size:
2.1 MB
File name:
PU01518CEN_0223.pdf
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PU (Publication)
効率的なバイオ医薬品の製品開発ライフサイクルのために拡張性を優先
この技術文書では、ライフサイエンス産業におけるバイオプロセス
の競争優位性としての拡張性の重要性と、Endress+Hauserの拡張性
のあるラマンシステム（Raman Rxn2、Raman Rxn4、Rxn-10、Rxn-45
、Rxn-46、バイオマルチオプティックおよびスリーブ、フローフィ
ル、フローベンチ、シングルユース用Ramanオプティックシステム）
、水質分析センサ技術、および水質分析製品ラインナップ
（LiquilineCM44P、CM442、OUSAF44、OUSBT66、Memosens CPS61E、
CLS82E、COS81E、CLS82E）について考察しています。Language:
Japanese
Version:
04/10/2024
File size:
1.3 MB
File name:
PU01584CJA_0124_Scalability in biopharma development.pdf
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-
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PU (Publication)
Endress+Hauser - your one-source Life Sciences technology partner
Graphic highlighting why Endress+Hauser is trusted by the
world's top biopharmaceutical manufacturers for its Life
Sciences expertise and reliable inline, real-time measurement
technologies like Raman spectroscopy systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology (Liquiline CM44P, CM442 and
OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E,
CLS82E).Language:
Czech
Version:
06/09/2024
File size:
353 KB
File name:
PU01585CEN_0124_cz_view.pdf
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PU (Publication)
Lab-to-process monitoring & control in Life Sciences - Reliable measurement of bioprocess physical and chemical properties
A combined product list of analysis offerings from both Optical Analysis
and LIquid Analysis for bioprocessing applications in the life science
industry (including Raman Rxn2 analyzer, Raman Rxn4 analyzer,
Rxn-10 probe, bio multi optic and bio sleeve, Raman flow assembly,
Rxn-45 probe, Rxn-46 probe, Raman optic system for single use,
Memosens CPS61E, Memosens COS81E, OUSBT66, Memosens CPS61E,
Memosens CPS77E, Memosens CLS82E, OUSAF44, Memosens CPS11E,
Memosens CLS16E, TOC Analyzer CA79, Liquiline transmitter platform, and
Memobase software).Language:
English
Version:
11/04/2024
File size:
776.1 KB
File name:
PU01484CEN_0224.pdf
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Competence Brochure (CP)
Raman single-use measurement precision - Real-time composition analysis for biopharmaceutical development and manufacturing with the Raman Rxn portfolio
An eBook highlighting our Raman spectroscopy reusable and
single-use bioprocessing portfolio (including the Raman Rxn2
analyzer, Raman Rxn4 analyzer, Rxn-10 probe, Rxn-46 probe,
Raman single use optic system, bio multi optic, and bio sleeve),
powered by Kaiser Raman technology.Language:
English
Version:
29/08/2024
File size:
1.2 MB
File name:
CP01586CEN_0124.pdf
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Competence Brochure (CP)
Faster market entry, higher yields, and improved quality - Real-time, inline bioprocess monitoring and control from lab to GMP with Raman Rxn systems & Memosens digital sensors
This eBook highlights the Endress+Hauser inline analysis portfolio
for bioprocessing including Raman spectroscopy systems
(Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic
and sleeve, flow cell and flow bench, Raman optic system for single use)
and liquid analysis sensor technology (Liquiline CM44P, CM442 and
OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E)
in the Life Science industry.Language:
English
Version:
21/06/2024
File size:
1.9 MB
File name:
CP01579CEN_0124.pdf
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Competence Brochure (CP)
Faster market entry, higher yields, and improved quality - Real-time, inline bioprocess monitoring and control from lab to GMP with Raman Rxn systems & Memosens digital sensors
This eBook highlights the Endress+Hauser inline analysis portfolio
for bioprocessing including Raman spectroscopy systems
(Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic
and sleeve, flow cell and flow bench, Raman optic system for single use)
and liquid analysis sensor technology (Liquiline CM44P, CM442 and
OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E)
in the Life Science industry.Language:
Czech
Version:
06/09/2024
File size:
1.7 MB
File name:
CP01579CEN_0124_cz_view.pdf
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Competence Brochure (CP)
市場投入の加速、歩留まりの増加、品質の向上 Raman RxnシステムとMemosensデジタルセンサによる、ラボからGMP までのリアルタイムでのインラインバイオプロセス監視と制御
この eBook では、ライフサイエンス業界におけるラマン分光シス
テム (Raman Rxn2、Raman Rxn4、Rxn-10、Rxn-45、Rxn-46、バイオ
マルチオプティックおよびスリーブ、フローセルおよびフローベン
チ、シングルユース向けラマンオプティックシステム) や水質分析
センサ技術 (Liquiline CM44P、CM442、OUSAF44、OUSBT66、
Memosens CPS61E、CLS82E、COS81E、CLS82E) を含む、バイオプロ
セス向けの Endress+Hauser インライン分析製品ラインナップを紹
介しています。Language:
Japanese
Version:
02/12/2024
File size:
5.7 MB
File name:
CP01579CJA_0124_Fast-entry-yields_Inline-monitoring_Raman-Memosens.pdf
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Innovation (IN)
Raman single-use technology for bioprocessing - Real-time composition analysis for biopharmaceutical development and manufacturing
An overview brochure about our Raman spectroscopy multi use and
single use bioprocessing portfolio (including the Raman Rxn2 analyzer,
Raman Rxn4 analyzer, Rxn-10 probe, Rxn-46 probe, Raman single use
optic system, bio multi optic, and bio sleeve), powered by Kaiser Raman
technology.Language:
English
Version:
13/12/2023
File size:
4 MB
File name:
IN01267CEN_0223.pdf
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Innovation (IN)
バイオプロセスにおけるラマン技術 - 拡張性のあるin situバイオプロセス監視と高度なプロセス制御
Kaiserラマンテクノロジーを搭載した、バイオプロセス/バイオ医
薬品業界向けのラマン分光アナライザーとプローブ製品ラインナッ
プ（ラマンRxn2アナライザー、ラマンRxn4アナライザー、Rxn-10プ
ローブ、Rxn-45プローブ、Rxn-46プローブ、プローブオプティック
アクセサリ（bIOオプティック、シングルユース向けラマンオプテ
ィックシステム、バイオマルチオプティックおよびバイオスリーブ
と組合せ、ラマンフローアセンブリを含む）の概要パンフレット。Language:
Japanese
Version:
02/08/2024
File size:
7.2 MB
File name:
IN01228CJA_0223_Raman technology in bioprocessing.pdf
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Innovation (IN)
Raman technology in bioprocessing - Scalable in situ bioprocess monitoring enabling advanced process control
An overview brochure about our Raman spectroscopy analyzer
and probe portfolio, powered by Kaiser Raman technology, for
the bioprocessing / biopharmaceutical industry (including the
Raman Rxn2 analyzer, Raman Rxn4 analyzer, Rxn-10 probe,
Rxn-45 probe, Rxn-46 probe, and probe accessory optics (bIO-Optic,
Raman single use optic system, bio multi optic with bio sleeve, and
Raman flow assembly), powered by Kaiser Raman technology.Language:
English
Version:
19/06/2023
File size:
6.8 MB
File name:
IN01228CEN_0223.pdf
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Innovation (IN)
Technologie Raman pour les bioprocédés
Surveillance évolutive des bioprocédés in situ et contrôle
avancé des processLanguage:
French
Version:
08/02/2024
File size:
1.3 MB
File name:
IN01228CFR-Raman bioprocedes.pdf
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Innovation (IN)
バイオプロセス用のラマンシングルユース技術 - バイオ医薬品の開発および製造のためのリアルタイム組成分析
Kaiserラマンテクノロジーを採用したラマン分光法マルチユースお
よびシングルユースバイオプロセス用製品ラインナップ（ラマン
Rxn2アナライザー、ラマンRxn4アナライザー、Rxn-10プローブ、
Rxn-46プローブ、シングルユース向けラマンオプティックシステム
、バイオマルチオプティック、バイオスリーブを含む）の概要パン
フレット。Language:
Japanese
Version:
02/08/2024
File size:
5.9 MB
File name:
IN01267CJA_0223_Raman_single-use_Tech_BioProc.pdf
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White paper (WP)
Revolutionizing biomanufacturing - Real-time, inline bioprocess measurement across the product lifecycle
This white paper examines the importance of
inline measurement techniques like Raman spectroscopy
systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45,
Rxn-46, bio multi optic and sleeve, flow cell and flow
bench, Raman optic system for single use) and liquid
analysis sensor technology (Liquiline CM44P, CM442 and
USAF44, OUSBT66 and Memosens CPS61E, CLS82E,
COS81E, CLS82E) to gain a bioprocessing competitive
advantage in the Life Science industry.Language:
Czech
Version:
06/09/2024
File size:
300.1 KB
File name:
WP01220CEN_0124_cz_view.pdf
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White paper (WP)
How Raman ensures product quality from lab-to-process in biopharma
A whitepaper about using Raman spectroscopy for lab-to-process
chemical composition measurement in biopharmaceutical manufacturing
(applicable to the Endress+Hauser Raman analyzer and probe
bioprocessing portfolio, powered by Kaiser Raman technology
(including the Raman Rxn2 analyzer, Raman Rxn4 analyzer,
Rxn-10 probe, Rxn-45 probe, Rxn-46 probe, bIO-Optic, Raman
single use optic system, immersion optic , non-contact optic).Language:
English
Version:
17/02/2022
File size:
350.8 KB
File name:
WP01172CEN_0222.pdf
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White paper (WP)
バイオマニュファクチャリングの革新 - 製品ライフサイクル全体にわたるリアルタイムのインラインバイオプロセス測定
このホワイトペーパーでは、ライフサイエンス産業におけるバイオ
プロセスの競争優位性を獲得するために、ラマン分光システム
（Raman Rxn2、Raman Rxn4、Rxn-10、Rxn-45、Rxn-46、バイオマル
チオプティックおよびスリーブ、フローフィル、フローベンチ、シ
ングルユース用Ramanオプティックシステム）や水質分析センサ技
術（Liquiline CM44P、CM442、USAF44、OUSBT66、Memosens CPS61E
、CLS82E、COS81E、CLS82E）といったインライン測定技術の重要性
について考察しています。Language:
Japanese
Version:
04/10/2024
File size:
2.3 MB
File name:
WP01220CJA_0124_Real-time inline bioprocess measurement.pdf
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-
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White paper (WP)
Revolutionizing biomanufacturing - Real-time, inline bioprocess measurement across the product lifecycle
This white paper examines the importance of
inline measurement techniques like Raman spectroscopy
systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45,
Rxn-46, bio multi optic and sleeve, flow cell and flow
bench, Raman optic system for single use) and liquid
analysis sensor technology (Liquiline CM44P, CM442 and
USAF44, OUSBT66 and Memosens CPS61E, CLS82E,
COS81E, CLS82E) to gain a bioprocessing competitive
advantage in the Life Science industry.Language:
English
Version:
27/06/2024
File size:
1.8 MB
File name:
WP01220CEN_0124.pdf
-