
Specs at a glance
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Wetted materials
Body: 316L stainless steel
Window: Proprietary material, optimized for bioprocesses
Surface finish: Ra 15 with Electropolish to ASME BPE SF4 finish
Adhesive: USP Class VI and ISO 10993 compatible -
Immersible length
120 or 220 mm
4.73 or 8.67 inch -
Sterilization method
Autoclave, gamma irradiation
Field of application
The bio sleeve is a critical consumable part for easy, real-time bioprocess measurements with maximum sterility and efficiency. It connects to a reusable, automatically aligned multi optic which pairs with an Rxn-10 probe. The system reduces maintenance and cross-contamination risk for reusable or single-use benchtop bioreactor setups.
Benchtop bioreactors to measure glucose, lactate, amino acids, cell density, titer and more
Benchtop fermenters to measure glycerol, methanol, ethanol, sorbitol, biomass, and more
Use with flow assembly CYA680 for select downstream bioprocessing applications
Benefits
Improved ease of use and reduced maintenance
Autoclavable, gamma sterilizable, and compatible with standard cleaning protocols
Simplified workflow for greater process efficiency – swap out probes mid-batch, use multiple sleeves in the same reactor for simplified redundancy, and calibrate / verify probes at any time
120 mm version is compatible with Endress+Hauser flow assembly CYA680
Extended selection
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High-end products
- Highly functional and convenient
Technical excellence
Simplicity

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Standard products
- Reliable, robust and low-maintenance
Technical excellence
Simplicity
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Specialized products
- Designed for demanding applications
Technical excellence
Simplicity
Variable
FLEX selections | Technical excellence | Simplicity |
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Fundamental selection Meet your basic measurement needs |
Technical excellence
|
Simplicity
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Lean selection Handle your core processes easily |
Technical excellence
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Simplicity
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Extended selection Optimize your processes with innovative technologies |
Technical excellence
|
Simplicity
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Xpert selection Master your most challenging applications |
Technical excellence
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Simplicity
Variable |
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Technical Information (TI)
Accessory optics for the Rxn-10 probe Technical Information
System design and specifications for Rxn-10 probe optics:
Raman immersion optics (KIO1),
non-contact optics (KNCO1), bIO-Optics (KLBIO1),
bio multi optics (KRBMO), bio sleeves (KRBSL),
and Raman optic system for single use (KRSU1)EN 31/05/202303/08/2022Language:
English
Version:
31/05/2023
File size:
467.9 KB
File name:
TI01635CEN_0322.pdf
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Technical Information (TI)
Multi optic calibration and verification kit Technical Information
System design and specifications for the multi optic calibration
and verification kitEN 26/06/2023Language:
English
Version:
26/06/2023
File size:
478.7 KB
File name:
TI01719CEN_0123 Multi optic calibration and verification kit.pdf
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Technical Information (TI)
Rxn-10 Raman spectroscopic probe Technical Information
System design and specifications for the Raman Rxn-10 probe
EN 13/11/202431/05/202313/09/202208/09/2021Language:
English
Version:
13/11/2024
File size:
929.9 KB
File name:
TI01629CEN_0424.pdf
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Operating Instruction (BA)
Accessory optics for the Rxn-10 probe Operating Instructions
Commissioning, operation, and maintenance details
for Rxn-10 probe optics: Raman immersion optics (KIO1),
non-contact optics (KNCO1), bIO-Optics (KLBIO1),
bio multi optics (KRBMO), bio sleeves (KRBSL)
and Raman optic system for single use (KRSU1)EN 31/05/202303/08/202214/09/2021Language:
English
Version:
31/05/2023
File size:
1.8 MB
File name:
BA02171CEN_0322.pdf
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Operating Instruction (BA)
Multi optic calibration and verification kit Operating Instructions
Commissioning, operation, and maintenance details for the
multi optic calibration and verification kitEN 26/06/2023Language:
English
Version:
26/06/2023
File size:
996.4 KB
File name:
BA02294CEN_0123 Multi optic calibration and verification kit.pdf
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Operating Instruction (BA)
Rxn-10 Raman spectroscopic probe Operating Instructions
Commissioning, operation, and maintenance details
for the Raman Rxn-10 probeEN 02/12/202431/05/202313/09/202208/09/2021Language:
English
Version:
02/12/2024
File size:
1.2 MB
File name:
BA02160CEN_0424.pdf
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Short Instruction (KA)
Rxn-10 Raman spectroscopic probe Brief Operating Instructions
Quick start guide for the Raman Rxn-10 probe
EN 02/12/202431/05/202313/09/202208/09/2021Language:
English
Version:
02/12/2024
File size:
1.6 MB
File name:
KA01546CEN_0424.pdf
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Short Instruction (KA)
Accessory optics for the Rxn-10 probe Brief Operating Instructions
Quickstart guide for Rxn-10 probe optics:
Raman immersion optics (KIO1),
non-contact optics (KNCO1), bIO-Optics (KLBIO1),
bio multi optics (KRBMO), bio sleeves (KRBSL),
and Raman optic system for single use (KRSU1)EN 31/05/202303/08/202214/09/2021Language:
English
Version:
31/05/2023
File size:
1 MB
File name:
KA01551CEN_0322.pdf
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PU (Publication)
Biopharma 4.0 model graphic
Graphic illustrating the core elements of Biopharma 4.0 including
product lifecycle stages, role of PAT/QbD, and 12 key advanced
technologies for scientists and process engineers in the Life
Sciences, applicable to Raman spectroscopy systems (Raman
Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and
sleeve, flow cell and flow bench, Raman optic system for single
use, and Raman calibration & verification kits).Language:
English
Version:
22/05/2025
File size:
481.6 KB
File name:
PU01614CEN_0125.pdf
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PU (Publication)
Prioritize scalability for an efficient biopharmaceutical product development lifecycle
This technical paper studies the importance of scalability as a
competitive advantage in bioprocessing in the Life Science industry,
and Endress+Hauser's scalable Raman systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology and Liquid Analysis portfolio
(Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and
Memosens CPS61E, CLS82E, COS81E, CLS82E).Language:
Czech
Version:
06/09/2024
File size:
381.4 KB
File name:
PU01584CEN_0124_cz_view.pdf
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